What is Leaky Bowel Syndrome?

Murat Balanlı, MD
16 January 2023

Leaky gut syndrome is a digestive problem that occurs for various reasons. This problem occurs when the tight junctions between the cell layers, which determine what can and cannot enter the bloodstream, are damaged. These junctions are the gateway between the intestines and the bloodstream. Under normal conditions, the tight junctions in the intestine only allow the passage of digested nutrients, minerals and vitamins, but when these junctions are opened, unwanted substances such as toxins, bacteria and undigested food particles also enter the bloodstream. Loosening of this structure is called 'leaky gut syndrome'.

If the immune system does not recognise the various microorganisms and particles that pass into the bloodstream, it can initiate an autoimmune reaction. Recent studies show that almost everyone with autoimmune disease has leaky gut syndrome, with or without symptoms.

Leaky gut syndrome can cause various symptoms. It can manifest itself with many symptoms such as food allergies, immune system diseases, skin problems, neurological problems, vitamin deficiencies, untreated depression, chronic headache, fibromyalgia, constipation, diarrhea, irritable bowel syndrome, chronic fatigue.

Some people do not experience any digestive symptoms despite the presence of leaky gut. Instead, swelling of the hands and feet after eating, muscle tension and stiffness in the morning, brain fog and distraction when certain foods are consumed.


What are the Factors Causing Leaky Bowel Syndrome?

  • Frequent use of antibiotics
  • Experiencing acute emotional or physical trauma
  • Chronic stress
  • Chronic dysbiosis
  • Use of non-steroidal anti-inflammatory drugs, ibuprofen or drugs that act in this way
  • Toxins
  • Liver toxicity and excess fat consumption
  • Alcohol dependence

Risk factors for the development of leaky gut include structural/anatomical problems, motility disorders, immunodeficiency, reduced digestive secretions and old age.

Which treatment methods should be used?

The most effective way to treat this gastrointestinal disorder is to follow the intestinal healing protocol (remove, replace, repair and rebalance). In this, it is important to eliminate foods and factors that damage the intestines and replace them with therapeutic foods. In addition, it is necessary to repair the gut with special supplements such as butyric acid and rebalance the microbiome with probiotics. Other factors that increase treatment success are reducing stress levels, improving sleep quality, and limiting smoking and alcohol consumption.

Page content is for informational purposes only. Consult your doctor for diagnosis and treatment.

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